Warmblood Fragile Foal Syndrome is an autosomal recessive disorder resulting in extremely fragile skin and abnormal laxity in the joints occurring, as the name suggests, primarily in Warmblood horses. The mutation occurs in the LH1 gene (also known as PLOD1). A foal must inherit the mutation from both parents to be affected.

A study of 500 Warmblood horses in Germany found that 9.5% of the horses were carriers or approximately 1 in 10 (Monthoux, et al. 2015)

The test allows the identification of carriers so that breeding two carriers together can be avoided. Animals carrying one copy of the mutation are unaffected.

The test can be performed using hair samples. Cost is $40 per sample.